No-Fenol was developed by Dr. Devin Houston in response to parents' request for a product that would allow their children to eat fruits and vegetables without the problems thought to be associated with polyphenolic compounds. Initial response from many parents indicate that for many, No-Fenol does allow the addition of these foods to the diet without complications.
All plants contain some degree of phenolic compounds. The phenol structure itself is ubiquitous in nature, and is actually essential to many of life's processes. Current thinking by many is that some subset of children on the PDD spectrum have difficulty in the processing of phenolic compounds, which may present as behavioral problems and physical symptoms such as red ears and cheeks, and dark circles under the eyes. While the basic mechanism behind this phenomenon is not well defined, it is thought that perhaps the phenolic compounds become "trapped" in some part of a metabolic cycle, presumbably involved with various detoxification pathways.
The research literature indicates that some phenolic compounds are modified by the addition of carbohydrate groups to their structures, which may inhibit their crossing into cells and being metabolized. The current hypothesis for why No-Fenol may help is through the ability of the enzymes in this product to remove the carbohydrate groups from the phenols, thus allowing normal processing by the detoxification pathways. There is no evidence that No-Fenol directly modifies phenolic structures. Indeed, the success of No-Fenol in allowing the addition of phenolic foods back into the diet of children with PDD may result in a re-evaluation of the basis of the phenol "problem".
Xylanase is the major component of No-Fenol, and is an enzyme used to breakdown the structural components of plant cell walls, which are primarily very complex carbohydrates. Xylanase is used in the juice industry to extract more juice from fruit pulp fibers. At least one reference indicates that polyphenolic compounds are actually increased by treatment with xylanase. Based on this reference and the fact that No-Fenol has allowed "phenol-sensitive" individuals to ingest phenolic foods, Houston Enzymes now believes that the phenol issue is much more complex than previously thought, and may not be due so much to the presence of phenols as to the specific structure of these phenols.
Filler No-Fenol capsules contains cellulose/medium-chain triglyceride oil (MCT oil) as filler. MCT oil is derived from palm oil, and the cellulose is derived from European Spruce trees. The capsule is also cellulose.
No-Fenol Capsules
Supplement Facts
Serving Size: 1 Capsule - Servings per Container: 90
OTHER INGREDIENTS: Vegetable capsule (cellulose and water), cellulose and Medium Chain Triglycerides. No added sugar, starch, dairy, soy, wheat, yeast, gluten, artificial flavors, or animal derivatives. CereCalase® is a registred trademark of National Enzyme Company.
Orders that are in stock are dispatched daily at 2pm Monday – Friday.
Orders placed before 2pm Monday to Friday will be dispatched the same day.
Orders placed after 2pm Monday to Friday will be dispatched the next working day.
As such, orders placed after 2pm Friday will be dispatched the following Monday.
Orders will not be dispatched on Bank Holidays or weekends.
For Standard Domestic Orders: We use Royal Mail’s Tracked 48hr delivery service as standard. Royal Mail state a delivery guideline of 1-2 working days for this service, however during busier periods (such as Christmas) this may not always be possible. If your order has not arrived after 2 working days from the date of dispatch please contact us. We have tracking numbers for this service and will be able to assist you in locating your order.
For Expedited Domestic Orders (Next-Day Delivery): Provided that we have received your order by 2pm, we will process and dispatch your order the same day using Royal Mail’s Tracked 24hr delivery service. This service aims to deliver your parcel within 24hrs of the dispatch time – in some instances this may not be possible and delivery may fall within a 48hr period. If you have not received your order after 1 day from the dispatch date please contact us. This is a tracked and insured service and we will be able to assist you in locating your order.
For Standard International Orders: We use Royal Mail International Track (+ Sign), dependent on what the destination country accepts. Royal Mail state a 3-5 working day delivery guideline for this service within Europe, and a 5-7 working day guideline worldwide. However, we have found this is rarely the case outside of major cities, especially during busier periods (such as Christmas) this may not always be possible. This is a tracked and insured service, please contact us if you have not received your delivery within the above stated time-frames and we will assist you in locating your order.
For Expedited International Orders: We are able to offer expedited international shipping worldwide respected couriers. We can use DHL or another courier of your choice, but we are likely to get the best deal from DHL. Please feel free to use the 'Contact Us' form to ask for a DHL quote for your order.
We are able to offer expedited delivery worldwide using various couriers; this is something that we will examine on a case-by-case basis. Please email us and we will investigate your delivery options and let you know what is possible.
If you have selected a shipping method that does not include tracking/insurance then you accept and agree that in the instance that the parcel is lost or delayed, you will not be entitled to a refund or a replacement product, as we will be unable to make a claim for the loss.
We retain proof of postage at all times and reserve the right to use a different shipping method than you have selected in order to give your order added security in certain circumstances (e.g. for extremely high value orders we may upgrade to Courier delivery). In the majority of situations we will respect the customers chosen shipping method. We retain proof of postage for 180 days. After this time it may not be possible to retrieve your proof of postage.
Standard International Orders are not considered 'lost' by postal carriers until 90 days after the dispatch. As such, we will not consider an order to be officially lost until this time has passed. We may consider an order lost before this date based on tracking information and our previous experiences, but this will be examined on a case-by-case basis.
